Research Article

Formulation of LDL Targeted Nanostructured Lipid Carriers Loaded with Paclitaxel: A Detailed Study of Preparation, Freeze Drying Condition, and In Vitro Cytotoxicity

Table 5

Results of a preliminary screening of different cryoprotectants.

CryoprotectantParticle size
(nm)
Zeta potential
(mV)

PEG40001550 ± 296.3−4.5 ± 0.3
Avicel RC591956 ± 120.6−6.9 ± 0.9
Mannitol1056 ± 213.6−2.8 ± 0.1
Dextrose857 ± 87.6−4.3 ± 0.4
Sorbitol216 ± 21.2−10.6 ± 0.7
Aerosil480 ± 83.2−15.6 ± 0.3