Formulation of LDL Targeted Nanostructured Lipid Carriers Loaded with Paclitaxel: A Detailed Study of Preparation, Freeze Drying Condition, and In Vitro Cytotoxicity

Table 6

IC₅₀ values of PTX solutions and the drug-loaded NLC against HT-29 cell lines.

Drug formulation	IC50 (mean ± SD)
	24 h	48 h	72 h
PTX in cremophor EL	15.81 ± 3.12	10.23 ± 1.56	8.32 ± 1.35
PTX-NLC	18.93 ± 2.56	11.24 ± 2.34	5.24 ± 0.96
PTX in DMSO	13.31 ± 4.12	8.93 ± 3.56	6.91 ± 0.85