Research Article

Pulmonary Toxicity, Distribution, and Clearance of Intratracheally Instilled Silicon Nanowires in Rats

Figure 3

Low magnification (a) and (b) and high magnification (c) and (d) field emission scanning electron micrographs of Si NW uptake by primary rat alveolar macrophages (AMs) in vitro after a 4-hour incubation with 25 μg of Si NW. AMs readily scavenged and engulfed both individual Si NW (a) as well as agglomerates of Si NW (b) (area of inset indicated by white arrows). The gold catalyst particle can also be seen at high magnification (red arrow head, (c) and (d)).
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