Pulmonary Toxicity, Distribution, and Clearance of Intratracheally Instilled Silicon Nanowires in Rats

Table 2

Morphometric analysis of connective tissue in rats treated with 100 μg of Si NW.

Treatment group	% of Alveolar wall	Thickness (μm)
DM Control	3.0±0.3	0.075±0.089
Si 100 Day 1	3.4±0.3	0.084±0.064
Si 100 Day 3	3.5±0.4	0.083±0.009
Si 100 Day 7	3.9±0.3	0.095±0.009
Si 100 Day 28	4.4±0.4^∗	0.110±0.012^∗
Si 100 Day 91	5.4±0.4^∗	0.135±0.010^∗

Note: *significantly elevated when compared to DM control group, 𝑃<0.05.