Nanomaterials for the Local and Targeted Delivery of Osteoarthritis Drugs

Figure 2

Features of polymeric micelles [21]. An amphiphilic copolymer in aqueous medium forms a micelle where the hydrophobic domains come together forming a core and hydrophilic domains forms the shell of the micelle. Hydrophobic drugs are entrapped in the core. Reactive functional groups at the micelle surface can be used to couple ligands for targeted delivery. Reproduced with permission from Elsevier.