Intra/Inter-Particle Energy Transfer of Luminescence Nanocrystals for Biomedical Applications
Figure 1
Single-step FRET-based QD biosensors designed to probe DNA degradation and protein. (a) The dsDNA (labeled with fluorescent dyes) degraded from QD surface compromises the FRET between dsDNA and QD. (b) The fluorescently labeled peptides, each with an enzyme-specific cleavage site, are bound to a QD and construct FRET. The FRET becomes decreasing as the enzyme starts to cleave the peptide into fragments.
