Study of Cytotoxic and Genotoxic Effects of Hydroxyl-Functionalized Multiwalled Carbon Nanotubes on Human Pulmonary Cells
Figure 4
Effects of 24 h exposure to 10, 20, 40, and 100 μg/mL of MWCNT-OH on A549 cells evaluated by Fpg-comet test. The histograms are related to the mean values of Tail moment (TM). Direct DNA damage is represented by mean TM value of cells untreated with Fpg enzyme. Oxidative DNA damage was evaluated subtracting TM mean values of cells untreated with Fpg enzyme (TM) from TM mean values of enzyme treated cells (TMenz) and is represented by TMenz-TM. The data represent the mean of three separate experiments. The statistical significance of differences between exposed and unexposed cells was calculated by non parametric Kruskal-Wallis test followed by post hoc T3 Dunnett’s test. *.
