Nanoscaffolds for Guided Cardiac Repair: The New Therapeutic Challenge of Regenerative Medicine
Figure 2
Cell sheet detachment from temperature-responsive culture surfaces. (a) ECM assures cell attachment to hydrophobic surfaces, and cell-to-cell junction proteins keep cells packed together; (b) enzymatic digestion causes ECM, and junctions are disrupted, and cells are released separately; (c) thermoresponsive culture surfaces allow the release of cell sheets by lowering temperature. Reproduced with permission of Wiley & Sons.
