Research Article

Retinoic Acid Decorated Albumin-Chitosan Nanoparticles for Targeted Delivery of Doxorubicin Hydrochloride in Hepatocellular Carcinoma

Table 2

Composition of different formulations investigated in preparation of doxorubicin loaded in RC-albumin nanoparticles using irregular factorial design.

Formulation codeTotal mass of RC-albumin (mg) (A)Albumin/RC (B)Drug/RC-albumin (C)Polymer type (D)

A100B1C0.5R210010.5R2
A10B0.5C0.5R2100.50.5R2
A10B0.5C0.25R2100.50.25R2
A100B0.5C0.5R41000.50.5R4
A100B0.5C0.5R21000.50.5R2
A10B1C0.5R21010.5R2
A100B1C0.25R210010.25R2
A100B0.5C0.25R41000.50.25R4
A10B1C0.5R41010.5R4
A100B1C0.25R410010.25R4
A10B0.5C0.25R4100.50.25R4
A10B1C0.25R41010.25R4