Retinoic Acid Decorated Albumin-Chitosan Nanoparticles for Targeted Delivery of Doxorubicin Hydrochloride in Hepatocellular Carcinoma

Table 3

Physicochemical properties of different doxorubicin-loaded RC-albumin nanoparticles.

Formulation code	Particle size (nm)	PdI	Zeta potential (mv)	Loading efficiency%	RE60%
A100B1C0.5R2	357.0±39.8	0.53	39.5±1.8	33.3±7.2	41.5±1.2
A10B0.5C0.5R2	232.4±19.3	0.31	43.7±1.2	40.6±14.5	66.6±128
A10B0.5C0.25R2	148.0±16.0	0.44	41.3±3.8	56.8±13.4	50.5±9.4
A100B0.5C0.5R4	264.5±86.7	0.77	46.8±3.2	8.3±2.8	76.8±2.4
A100B0.5C0.5R2	472.2±78.9	0.94	44.8±1.9	7.3±6.3	55.6±3.1
A10B1C0.5R2	370.0±51.9	0.93	29.3±6.9	50.7±4.7	52.6±7.8
A100B1C0.25R2	234.0±8.0	0.86	45.0±2.2	28.9±9.9	54.8±10.6
A100B0.5C0.25R4	340.7±64.6	0.76	41.2±4.7	32.5±6.8	32.2±4.2
A10B1C0.5R4	188.0±65.8	0.94	37.4±6.6	57.7±7.1	43.4±3.6
A100B1C0.25R4	349.0±65.3	0.70	42.3±2.3	34.2±5.1	53.8±8.1
A10B0.5C0.25R4	248.2±59.3	0.65	43.3±4.2	48.7±8.0	72±8.7
A10B1C0.25R4	186.4±18.3	0.74	42.5±0.3	41.1±26.2	46.4±5.4