[Retracted] Microwave Mediated Organic Reaction: A Convenient Approach for Rapid and Efficient Synthesis of Biologically Active Substituted 1,3-Dihydro-2H-indol-2-one Derivatives

Table 4

Anthelmintic activity of the synthesized Mannich bases (M₁–M₈).

Compounds	Concentration (mg/mL)	Time of paralysis (min); Mean ± SD	Time of death (min); Mean ± SD
M1	10	60±0.18	158±0.19
	20	57±0.14	145±0.24
	50	53±0.32	139±0.34
M2	10	48±0.24	134±0.27
	20	41±0.33	128±0.33
	50	37±0.16	115±0.32
M3	10	57±0.39	152±0.17
	20	53±0.34	148±0.43
	50	48±0.24	142±0.21
M4	10	64±0.33	156±0.35
	20	61±0.31	140±0.34
	50	57±0.42	137±0.51
M5	10	66±0.35	165±0.28
	20	63±0.42	143±0.34
	50	60±0.51	140±0.34
M6	10	64±0.19	186±0.29
	20	61±0.35	175±0.21
	50	58±0.25	157±0.36
M7	10	57±0.39	177±0.51
	20	53±0.32	163±0.33
	50	51±0.31	148±0.15
M8	10	60±0.29	191±0.33
	20	57±0.19	176±0.15
	50	52±0.52	169±0.19
Control; (normal saline)	No effects for 10 hours
Standard (albendazole)	10	49±0.56	68±0.21
	20	44±0.15	62±0.31
	50	38±0.21	53±0.24