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Journal of Nanomaterials
Volume 2013 (2013), Article ID 450483, 9 pages
http://dx.doi.org/10.1155/2013/450483
Obtaining of Sol-Gel Ketorolac-Silica Nanoparticles: Characterization and Drug Release Kinetics
1Laboratorio de Nanotecnología y Nanomedicina, Departamento de Atención a la Salud, Universidad Autónoma Metropolitana Xochimilco, Calzada del Hueso 1100, Col. Villa Quietud, Delegación Coyoacán, 04960 México, DF, Mexico
2Laboratorio de Nanotecnología, Instituto Nacional de Neurología y Neurocirugía “Manuel Velasco Suárez”, Avenida Insurgentes sur 3877, Col. La Fama, 14269 Tlalpan, DF, Mexico
3Department of Chemical and Biomolecular Engineering, Tulane University, New Orleans, LA 70118, USA
4Facultad de Ciencias, Universidad Nacional Autónoma de México, Avenida Universidad 3000, Circuito Exterior S/N Delegación Coyoacán, Ciudad Universitaria, 04510 México, DF, Mexico
Received 24 August 2012; Accepted 1 November 2012
Academic Editor: Yan-Yan Song
Copyright © 2013 T. M. López Goerne et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Linked References
- R. Bawa, “Patents and nanomedicine,” Nanomedicine, vol. 2, no. 3, pp. 351–374, 2007. View at Publisher · View at Google Scholar · View at Scopus
- R. Bawa, S. R. Bawa, S. B. Maebius, T. Flynn, and C. Wei, “Protecting new ideas and inventions in nanomedicine with patents,” Nanomedicine, vol. 1, no. 2, pp. 150–158, 2005. View at Publisher · View at Google Scholar · View at Scopus
- A. Abdulwahed, “Gastrointestinal and cardiovascular risk of nonsteroidal anti-inflammatory drugs,” Oman Medical Journal, vol. 26, no. 6, pp. 385–391, 2011. View at Publisher · View at Google Scholar
- L. Filaretova, T. Bagaeva, O. Morozova, and D. Zelena, “The healing of nsaid-induced gastric lesion may be followed by small intestinal and cardiovascular side effects,” Journal of Physiology and Pharmacology, vol. 62, no. 6, pp. 619–625, 2011.
- I. Pountos, T. Georgouli, G. Calori, and P. Giannoudis, “Do nonsteroidal anti-inflammatory drugs affect bone healing?” The Scientific World Journal, vol. 2012, Article ID 606404, 14 pages, 2012. View at Publisher · View at Google Scholar
- N. M. Gajraj, “The effect of cyclooxygenase-2 inhibitors on bone healing,” Regional Anesthesia and Pain Medicine, vol. 28, no. 5, pp. 456–465, 2003. View at Publisher · View at Google Scholar · View at Scopus
- L. E. Targownik, C. J. Metge, S. Leung, and D. G. Chateau, “The relative efficacies of gastroprotective strategies in chronic users of nonsteroidal anti-inflammatory drugs,” Gastroenterology, vol. 134, no. 4, pp. 937–e1, 2008. View at Publisher · View at Google Scholar · View at Scopus
- J. Varshosaz, V. Hajhashemi, and S. Soltanzadeh, “Lipid nanocapsule-based gels for enhancement of transdermal delivery of ketorolac tromethamine,” Journal Drug Delivery, vol. 2011, Article ID 571272, 7 pages, 2011. View at Publisher · View at Google Scholar
- P. Santhosh, N. Senthil Kumar, M. Renukadevi, A. I. Gopalan, T. Vasudevan, and K. P. Lee, “Enhanced electrochemical detection of ketorolac tromethamine at polypyrrole modified glassy carbon electrode,” Analytical Sciences, vol. 23, no. 4, pp. 475–478, 2007. View at Publisher · View at Google Scholar · View at Scopus
- S. Hungund and R. Thakkar, “Effect of pretreatment with Ketorolac Tromethamine on operative pain during periodontal surgery: a case-control study,” Journal of Indian Society of Periodontology, vol. 15, no. 1, pp. 55–58, 2011. View at Publisher · View at Google Scholar
- S. K. Paliwal, R. Chauhan, V. Sharma, D. K. Majumdar, and S. Paliwal, “Entrapment of ketorolac tromethamine in polymeric vehicle for controlled drug delivery,” Indian Journal of Pharmaceutical Sciences, vol. 71, no. 6, pp. 687–691, 2009. View at Publisher · View at Google Scholar · View at Scopus
- M. A. Radwan, B. T. AlQuadeib, N. M. Aloudah, and H. Y. Aboul Enein, “Pharmacokinetics of ketorolac loaded to polyethylcyanoacrylate nanoparticles using UPLC MS/MS for its determination in rats,” International Journal of Pharmaceutics, vol. 397, no. 1-2, pp. 173–178, 2010. View at Publisher · View at Google Scholar · View at Scopus
- V. R. Sinha and A. Trehan, “Formulation, characterization, and evaluation of ketorolac tromethamine-loaded biodegradable microspheres,” Drug Delivery, vol. 12, no. 3, pp. 133–139, 2005. View at Publisher · View at Google Scholar · View at Scopus
- A. P. Rokhade, S. A. Agnihotri, S. A. Patil, N. N. Mallikarjuna, P. V. Kulkarni, and T. M. Aminabhavi, “Semi-interpenetrating polymer network microspheres of gelatin and sodium carboxymethyl cellulose for controlled release of ketorolac tromethamine,” Carbohydrate Polymers, vol. 65, no. 3, pp. 243–252, 2006. View at Publisher · View at Google Scholar · View at Scopus
- L. Genc and E. Jalvand, “Preparation and in vitro evaluation of controlled release hydrophilic matrix tablets of ketorolac tromethamine using factorial design,” Drug Development and Industrial Pharmacy, vol. 34, no. 8, pp. 903–910, 2008. View at Publisher · View at Google Scholar · View at Scopus
- T. López, S. Recillas, P. Guevara, J. Sotelo, M. Alvarez, and J. A. Odriozola, “Pt/TiO2 brain biocompatible nanoparticles: GBM treatment using the C6 model in Wistar rats,” Acta Biomaterialia, vol. 4, no. 6, pp. 2037–2044, 2008. View at Publisher · View at Google Scholar · View at Scopus
- K. Farrington and F. Regan, “Molecularly imprinted sol gel for ibuprofen: an analytical study of the factors influencing selectivity,” Talanta, vol. 78, no. 3, pp. 653–659, 2009. View at Publisher · View at Google Scholar · View at Scopus
- J. Gonzáles, J. Pérez, F. Ruiz, and J. y Martínez, “Vidrios SiO2 nanocompuestos preparados por sol-gel: revisión,” Superficies y Vacío, vol. 11, pp. 1–16, 2000.
- J. Livage, C. Sanchez, M. Henry, and S. Doeuff, “The chemistry of the sol-gel process,” Solid State Ionics, vol. 32-33, no. 2, pp. 633–638, 1989. View at Scopus
- J. Livage, “Sol-gel processes,” Current Opinion in Solid State and Materials Science, vol. 2, no. 2, pp. 132–138, 1997. View at Scopus
- A. Kalampounias, “IR and Raman spectroscopic studies of sol-gel derived alkaline-earth silicate glasses,” Bulletin of Materials Science, vol. 34, no. 2, pp. 299–303, 2011.
- C. M. Whang, C. S. Yeo, and Y. H. Kim, “Preparation and characterization of sol-gel derived SiO2-TiO2-PDMS composite films,” Bulletin of the Korean Chemical Society, vol. 22, no. 12, pp. 1366–1370, 2001. View at Scopus
- Y. T. Sohn and O. S. Hyun, “Crystal forms of ketorolac,” Archives of Pharmacal Research, vol. 27, no. 3, pp. 357–360, 2004. View at Scopus
- W. Lin and Zhong, Characterization of Nanophase Materials, Transmission Electron Microscopy and Spectroscopy of Nanoparticles, Qilwy-VCH Verlag GmbH, Berlin, Germany, 2000.
- M. J. Uddin, D. Mondal, C. A. Morris, T. Lopez, U. Diebold, and R. D. Gonzalez, “An in vitro controlled release study of valproic acid encapsulated in a titania ceramic matrix,” Applied Surface Science, vol. 257, no. 18, pp. 7920–7927, 2011. View at Publisher · View at Google Scholar · View at Scopus
- H. Guo, H. Qian, S. Sun et al., “Hollow mesoporous silica nanoparticles for intracellular delivery of fluorescent dye,” Chemistry Central Journal, vol. 5, no. 1, p. 1, 2011. View at Publisher · View at Google Scholar · View at Scopus
- K. Ruckmani, M. S. Muneera, and R. Vijaya, “Eudragit matrices for sustained release of ketorolac tromethamine: formulation and kinetics of release,” Bollettino Chimico Farmaceutico, vol. 139, no. 5, pp. 205–208, 2000.