Table 2:
Linearization coefficients obtained from in vitro release of Ketorolac from SiO
2
.
Reservoir
Zero-order
First-order
Higuchi
Hixon-crowel
Hyperbola
Ketorolac SiO
2
1 : 8
0.4183
0.6809
0.5980
0.5712
0.9651
Ketorolac SiO
2
1 : 4
0.7496
0.9664
0.8644
0.8919
0.9516
: amount of drug released in time
t
.
: initial amount of drug in the tablet.
,
,
,
: release rate constants.
b
: shape parameter.
a
: scale parameter.