About this Journal Submit a Manuscript Table of Contents
Journal of Nanomaterials
Volume 2013 (2013), Article ID 476585, 9 pages
Research Article

Antibacterial Properties of Titanate Nanofiber Thin Films Formed on a Titanium Plate

1Department of Chemistry and Applied Chemistry, Faculty of Science and Engineering, Saga University, 1 Honjo, Saga 840-8502, Japan
2Japan Medical Materials Corporation, Uemura Nissei Building 9F 3-3-31 Miyahara, Yodogawa-ku, Osaka 532-0003, Japan
3Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, 5 Nabeshima, Saga 849-8501, Japan

Received 16 January 2012; Accepted 25 September 2012

Academic Editor: Gajanan S. Bhat

Copyright © 2013 Mitsunori Yada et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A sodium titanate nanofiber thin film and a silver nanoparticle/silver titanate nanofiber thin film formed on the surface of a titanium plate exhibited strong antibacterial activities against methicillin-resistant Staphylococcus aureus, which is one of the major bacteria causing in-hospital infections. Exposure of the sodium titanate nanofiber thin film to ultraviolet rays generated a high antibacterial activity due to photocatalysis and the sodium titanate nanofiber thin film immediately after its synthesis possessed a high antibacterial activity even without exposure to ultraviolet rays. Elution of silver from the silver nanoparticle/silver titanate nanofiber thin film caused by the silver ion exchange reaction was considered to contribute substantially to the strong antibacterial activity. The titanate nanofiber thin films adhered firmly to titanium. Therefore, these titanate nanofiber thin film/titanium composites will be extremely useful as implant materials that have excellent antibacterial activities.