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Journal of Nanomaterials
Volume 2013 (2013), Article ID 495708, 11 pages
http://dx.doi.org/10.1155/2013/495708
Review Article

Electrospinning of Nanofibers for Tissue Engineering Applications

1Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Xue Yuan Road No. 37, Haidian District, Beijing 100191, China
2Orthopaedic Department, First Affiliated Hospital, PLA General Hospital, Beijing 100048, China

Received 9 June 2013; Accepted 26 June 2013

Academic Editor: Xiaoming Li

Copyright © 2013 Haifeng Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Electrospinning is a method in which materials in solution are formed into nano- and micro-sized continuous fibers. Recent interest in this technique stems from both the topical nature of nanoscale material fabrication and the considerable potential for use of these nanoscale fibres in a range of applications including, amongst others, a range of biomedical applications processes such as drug delivery and the use of scaffolds to provide a framework for tissue regeneration in both soft and hard tissue applications systems. The objectives of this review are to describe the theory behind the technique, examine the effect of changing the process parameters on fiber morphology, and discuss the application and impact of electrospinning on the fields of vascular, neural, bone, cartilage, and tendon/ligament tissue engineering.