Research Article
Physicochemical Properties and In Vitro Cytotoxicity Studies of Chitosan as a Potential Carrier for Dicer-Substrate siRNA
Table 1
Particle size, PDI, and zeta potential of DsiRNA-CS NPs/complexes,
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| CS concentration (% /) | Simple complexation | Adsorption | Particle size (nm) ± SD | PDI ± SD | Zeta potential (mV) ± SD | Particle size (nm) ± SD | PDI ± SD | Zeta potential (mV) ± SD |
| 0.1 | 270.33 ± 56.14 | 0.60 ± 0.06 | +56.77 ± 7.64 | 216.37 ± 45.52 | 0.59 ± 0.06 | +40.50 ± 2.95 | 0.2 | 404.13 ± 10.64 | 0.75 ± 0.17 | +57.10 ± 6.22 | 231.00 ± 68.78 | 0.52 ± 0.18 | +46.13 ± 4.21 | 0.3 | 624.67 ± 64.90 | 0.69 ± 0.08 | +68.50 ± 1.87 | 251.23 ± 33.80 | 0.53 ± 0.10 | +37.27 ± 6.07 | 0.4 | 734.40 ± 73.73 | 0.72 ± 0.19 | +69.23 ± 5.05 | 336.50 ± 11.38 | 0.74 ± 0.12 | +61.30 ± 4.91 |
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