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Journal of Nanomaterials
Volume 2013 (2013), Article ID 958172, 8 pages
http://dx.doi.org/10.1155/2013/958172
Research Article

In Vitro Biocompatibility of Electrospun Chitosan/Collagen Scaffold

1Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China
2Clinical Institute of Integrative Chinese and Western Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai 200437, China
3Department of Textile and Chemical Engineering, Changzhou Textile Garment Institute, Changzhou 213164, China

Received 14 June 2013; Revised 31 July 2013; Accepted 22 August 2013

Academic Editor: Xiaoming Li

Copyright © 2013 Peiwei Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. V. L. Roger, A. S. Go, D. M. Lloyd-Jones, et al., “Heart disease and stroke statistics-2012 update: a report from the American Heart Association,” Circulation, vol. 125, no. 1, pp. e2–e220, 2012.
  2. L. G. Griffith and G. Naughton, “Tissue engineering—current challenges and expanding opportunities,” Science, vol. 295, no. 5557, pp. 1009–1014, 2002. View at Publisher · View at Google Scholar · View at Scopus
  3. B. C. Isenberg, C. Williams, and R. T. Tranquillo, “Small-diameter artificial arteries engineered in vitro,” Circulation Research, vol. 98, no. 1, pp. 25–35, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. X. Wang, P. Lin, Q. Yao, and C. Chen, “Development of small-diameter vascular grafts,” World Journal of Surgery, vol. 31, no. 4, pp. 682–689, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. H. Kurobe, M. W. Maxfield, C. K. Breuer, and T. Shinoka, “Concise review: tissue-engineered vascular grafts for cardiac surgery: past, present, and future,” Stem Cells Translational Medicine, vol. 1, no. 7, pp. 566–571, 2012.
  6. X. Li, H. Liu, X. Niu et al., “The use of carbon nanotubes to induce osteogenic differentiation of human adipose-derived MSCs in vitro and ectopic bone formation in vivo,” Biomaterials, vol. 33, no. 19, pp. 4818–4827, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. Z. Ma, Z. Mao, and C. Gao, “Surface modification and property analysis of biomedical polymers used for tissue engineering,” Colloids and Surfaces B, vol. 60, no. 2, pp. 137–157, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. E. Khor and L. Y. Lim, “Implantable applications of chitin and chitosan,” Biomaterials, vol. 24, no. 13, pp. 2339–2349, 2003. View at Publisher · View at Google Scholar · View at Scopus
  9. W. W. Thein-Han, Y. Kitiyanant, and R. D. K. Misra, “Chitosan as scaffold matrix for tissue engineering,” Materials Science and Technology, vol. 24, no. 9, pp. 1062–1075, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. A. Sarasam and S. V. Madihally, “Characterization of chitosan-polycaprolactone blends for tissue engineering applications,” Biomaterials, vol. 26, no. 27, pp. 5500–5508, 2005. View at Publisher · View at Google Scholar · View at Scopus
  11. J. A. Matthews, G. E. Wnek, D. G. Simpson, and G. L. Bowlin, “Electrospinning of collagen nanofibers,” Biomacromolecules, vol. 3, no. 2, pp. 232–238, 2002. View at Publisher · View at Google Scholar · View at Scopus
  12. J. Glowacki and S. Mizuno, “Collagen scaffolds for tissue engineering,” Biopolymers, vol. 89, no. 5, pp. 338–344, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. W. Tan, R. Krishnaraj, and T. A. Desai, “Evaluation of nanostructured composite collagen—chitosan matrices for tissue engineering,” Tissue Engineering, vol. 7, no. 2, pp. 203–210, 2001. View at Publisher · View at Google Scholar · View at Scopus
  14. X. M. Li, Y. Yang, Y. B. Fan, et al., “Biocomposites reinforced by fibers or tubes as scaffolds for tissue engineering or regenerative medicine,” Journal of Biomedical Materials Research Part A, 2013. View at Publisher · View at Google Scholar
  15. N. Bhardwaj and S. C. Kundu, “Electrospinning: a fascinating fiber fabrication technique,” Biotechnology Advances, vol. 28, no. 3, pp. 325–347, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. Z. G. Chen, P. W. Wang, B. Wei, X. M. Mo, and F. Z. Cui, “Electrospun collagen-chitosan nanofiber: a biomimetic extracellular matrix for endothelial cell and smooth muscle cell,” Acta Biomaterialia, vol. 6, no. 2, pp. 372–382, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. X. M. Li, L. Wang, Y. B. Fan, Q. L. Feng, and F. Z. Cui, “Biocompatibility and toxicity of nanoparticles and nanotubes,” Journal of Nanomaterials, vol. 2012, Article ID 548389, 19 pages, 2012. View at Publisher · View at Google Scholar
  18. G. Zund, Q. Ye, S. P. Hoerstrup et al., “Tissue engineering in cardiovascular surgery: MTT, a rapid and reliable quantitative method to assess the optimal human cell seeding on polymeric meshes,” European Journal of Cardio-thoracic Surgery, vol. 15, no. 4, pp. 519–524, 1999. View at Publisher · View at Google Scholar · View at Scopus
  19. L. Ma, C. Gao, Z. Mao et al., “Collagen/chitosan porous scaffolds with improved biostability for skin tissue engineering,” Biomaterials, vol. 24, no. 26, pp. 4833–4841, 2003. View at Publisher · View at Google Scholar · View at Scopus
  20. Y. Huang, M. Siewe, and S. V. Madihally, “Effect of spatial architecture on cellular colonization,” Biotechnology and Bioengineering, vol. 93, no. 1, pp. 64–75, 2006. View at Publisher · View at Google Scholar · View at Scopus
  21. B. G. Keselowsky, D. M. Collard, and A. J. García, “Surface chemistry modulates focal adhesion composition and signaling through changes in integrin binding,” Biomaterials, vol. 25, no. 28, pp. 5947–5954, 2004. View at Publisher · View at Google Scholar · View at Scopus
  22. X. Li, H. Gao, M. Uo et al., “Maturation of osteoblast-like SaoS2 induced by carbon nanotubes,” Biomedical Materials, vol. 4, no. 1, Article ID 015005, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. X. M. Li, L. Wang, Y. B. Fan, et al., “Nanostructured scaffolds for bone tissue engineering,” Journal of Biomedical Materials Research Part A, vol. 101, no. 8, pp. 2424–2435, 2013.
  24. X. Li, H. Gao, M. Uo et al., “Effect of carbon nanotubes on cellular functions in vitro,” Journal of Biomedical Materials Research A, vol. 91, no. 1, pp. 132–139, 2009. View at Publisher · View at Google Scholar · View at Scopus
  25. D. Bouïs, G. A. P. Hospers, C. Meijer, G. Molema, and N. H. Mulder, “Endothelium in vitro: a review of human vascular endothelial cell lines for blood vessel-related research,” Angiogenesis, vol. 4, no. 2, pp. 91–102, 2001. View at Publisher · View at Google Scholar · View at Scopus
  26. S. Meng, Z. Liu, L. Shen et al., “The effect of a layer-by-layer chitosan-heparin coating on the endothelialization and coagulation properties of a coronary stent system,” Biomaterials, vol. 30, no. 12, pp. 2276–2283, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. X. Li, Y. Fan, and F. Watari, “Current investigations into carbon nanotubes for biomedical application,” Biomedical Materials, vol. 5, no. 2, Article ID 022001, 2010. View at Publisher · View at Google Scholar · View at Scopus