Research Article

Photothermal Therapy Using Gold Nanorods and Near-Infrared Light in a Murine Melanoma Model Increases Survival and Decreases Tumor Volume

Figure 1

Transmission electron microscopy (TEM) analysis of GNRs before and after PEGylation and UV-Vis spectra of PEGylated GNRS. The GNRs are tuned to absorb NIR light by altering length to width ratios and the absorbed light is emitted as heat. (a) TEM image of GNRs before the addition of PEG. These GNRs are coated with CTAB. (b) TEM image of GNRs after PEGylation, with phosphotungstic acid staining to show PEG bilayer. (c) UV-Vis absorbance spectra for PEGylated GNRs, showing the LSPR at 850 nm.
450670.fig.001a
(a)
450670.fig.001b
(b)
450670.fig.001c
(c)