Synthesis and Characterization of Chitosan-Saponin Nanoparticle for Application in Plasmid DNA Delivery

Figure 7

Protective capacity of CS-SP nanoparticle against enzymatic degradation of DNA plasmid. Lane 1: 1 kb ladder (Viventis, Malaysia); lane 2: naked untreated DNA; lane 3: CS-SP-DNA without enzymatic treatment; lane 4: naked DNA treated with DNASE1; lane 5: CS-DNA-SP treated with DNASE1; lane 6: CS-SP-DNA treated with chitosanase which removes the chitosan protection and exposes the DNA plasmid.