Research Article
Preparation of Mesoporous Silica-Supported Chiral Amino Alcohols for the Enantioselective Addition of Diethylzinc to Aldehyde and Asymmetric Transfer Hydrogenation to Ketones
Table 3
Asymmetric transfer hydrogenation of ketones using immobilized ligands 2ba.
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||
The reactions were carried out at room temperature in 2-propanol; ketone : Ru : ligand : KOH = 100 : 1 : 2 : 5. bAcp = acetophenone and Pp = propiophenone. cDetermined by GC analysis. dDetermined by HPLC analysis using Chiralcel OD-H column (3% of 2-propanol in hexane, 1 mL/min). eThe catalyst was reused two times. f[RuCl2(hexamethylbenzene)]2 was used instead of [RuCl2(-cymene)]2. |