Research Article

Preparation and Evaluation of PEGylated and Folate-PEGylated Liposomes Containing Paclitaxel for Lymphatic Delivery

Table 2

The changes of liposomal size and encapsulation efficiency of PEGylated and folate-PEGylated liposomes at 4°C for 120 hours#.

Time (hour)Liposomal size (nm)Encapsulation efficiency (%)
PEGylated liposomeFolate-PEGylated liposomePEGylated liposomeFolate-PEGylated liposome

0114 ± 6.81122 ± 4.8781 ± 2.388 ± 2.0
24115 ± 4.26128 ± 5.0281 ± 2.086 ± 1.3
48115 ± 2.57128 ± 4.3880 ± 3.588 ± 1.4
72114 ± 3.91129 ± 4.2680 ± 3.186 ± 1.8
96115 ± 4.44129 ± 4.2479 ± 3.086 ± 1.1
120115 ± 2.71128 ± 6.8479 ± 1.885 ± 2.5

Mean ± S.D. ( = 5).