Formulation and Optimization of Eudragit RS PO-Tenofovir Nanocarriers Using Box-Behnken Experimental Design

Figure 4

D response surface plots showing the effect of (a) ratio of a polymer to a drug () and concentration of a surfactant () at constant sonication time () and (b) ratio of a polymer to a drug () and sonication time () at constant concentration of a surfactant ().

(a)

(b)