Formulation and Optimization of Eudragit RS PO-Tenofovir Nanocarriers Using Box-Behnken Experimental Design

Table 2

BBD experimental parameters and levels for preparation of nanoparticles.

Run
	Ratio of a polymer to a drug (mg)	Concentration of a surfactant (% SDS)	Sonication time (min)
1	50	3	45
2	50	5	45
3	100	3	45
4	100	5	45
5	50	4	30
6	50	4	60
7	100	4	30
8	100	4	60
9	75	3	30
10	75	3	60
11	75	5	30
12	75	5	60
13	75	4	45
14	75	4	45
15	75	4	45