Research Article
Attenuating Immune Response of Macrophage by Enhancing Hydrophilicity of Ti Surface
Figure 4
The influence of surface hydrophilicity on cell morphology and FBGCs formation. (a) Scanning electron microscopy images of macrophages cultured on Ti-polished or Ti-H2O2 surfaces for 1, 3, and 7 days. (b) The cytoskeleton organization of macrophages cultured on Ti-polished and Ti-H2O2 surfaces for 7 days. White asterisks indicate FBGCs. White arrow indicates the spindle cells. F-actin and cell nuclei were immunostained with Alexa Fluor 546-phalloidin (red) and DAPI (blue), respectively.
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