In Vitro and In Vivo Enhancement of Antitumoral Activity of Liposomal Antisense Oligonucleotides by Cineole as a Chemical Penetration Enhancer

<div>Epifluorescence microscopy study of FITC-antisense oligodeoxynucleotides (AsODN) cellular distribution. Cytoplasmic distribution of fluorescein green fluorescence (right images) was demonstrated after 4-hour incubation with either free AsODN (a, b), liposomal AsODN (c, d), cineole-treated free AsODN (b), and cineole-treated liposomal AsODN (d). Left images illustrate DAPI-stained nucleuses of the same systems.</div>

Journal of Nanomaterials

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Figure 4: In Vitro and In Vivo Enhancement of Antitumoral Activity of Liposomal Antisense Oligonucleotides by Cineole as a Chemical Penetration Enhancer 

Figure 4 | In Vitro and In Vivo Enhancement of Antitumoral Activity of Liposomal Antisense Oligonucleotides by Cineole as a Chemical Penetration Enhancer 