Chitosan-Alginate Nanoparticle System Efficiently Delivers Doxorubicin to MCF-7 Cells

Table 1

The size, zeta potential, and % EE of DOX Csn and DOX Csn-Alg NPs. All analyses were performed using the DOX loaded NPs prepared by using optimized formulations (chitosan : STTP 2 : 1 and chitosan : alginate 2 : 1).

System	Average size/nm	Zeta potential/mV	% Encapsulation efficiency	Polydispersity index
DOX Csn NPs	100 ± 27	26 ± 3	65 ± 4	0.391 ± 0.048
DOX Csn-Alg NPs	100 ± 35	35 ± 4	95 ± 4	0.402 ± 0.071
Csn NPs	100 ± 25	30 ± 5	—	0.352 ± 0.046
Csn-Alg NPs	100 ± 28	36 ± 3	—	0.414 ± 0.065