Review Article

Nanomechanical Characterization of Amyloid Fibrils Using Single-Molecule Experiments and Computational Simulations

Figure 3

AFM peak force QNM- (quantitative nanomechanical mapping-) based experiments of -synuclein amyloid fibrils. (a) and (c) show the AFM topographic images of the fibrils, while (b) and (d) present the AFM peak force QNM images of the fibrils. Here, (a) and (b) are obtained from AFM QNM experiments of the fibrils in liquid environment, while (c) and (d) are acquired based on AFM QNM imaging of the fibrils in ambient condition. Figures are adopted from [20] under Creative Commons Attribution (CCA).
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