Evaluation of Biomarkers of NAFLD in a Cohort of Morbidly Obese Patients
Figure 3
Association between apoptosis and fibrosis. Although fibrosis, as quantified by a pathologist in H&E sections is not increased in NASH, collagen staining and serum hyaluronic acid indicate more fibrosis in NASH (a). Hepatocyte apoptosis and serum hyaluronic acid are increased in advanced fibrosis (b, c). Cell death rate is associated with fibrotic areal in histological slides from NASH patients (d). Hyaluronic acid is correlated with serum cleaved CK18 (e). Linear increase in publications/year on serum markers of NAFLD (f).
