Research Article

Effects of Exercise Training on Molecular Markers of Lipogenesis and Lipid Partitioning in Fructose-Induced Liver Fat Accumulation

Figure 1

Gene expression of hepatic stearoyl-CoA desaturase1 (SCD1), sterol regulatory element-binding protein1c (SREBP1c), endocannabinoid receptors (CB1 and CB2), fatty acid amide hydrolase (FAAH), and protein content of liver SCD1 relative to β-actin in sedentary (Sed) and trained (TR) rats submitted to a fast/refeeding protocol. Animals were fed a standard (SD) diet during 7 wks and thereafter were starved for 24 h and fed with the SD diet for 24 h and starved for another 24 h and then fed with the SD or the high-fructose (HFr) diet 24 h prior to sacrifice at the end of the 8th week. Values are means ± SE with 𝑛 = 1 0  rats/group except for SCD1 protein level ( 𝑛 = 4–6 rats/group). &: significantly different from corresponding values under the SD diet, 𝑃 < 0 . 0 5 , &&: 𝑃 < 0 . 0 1 .
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