Research Article

Effects of Exercise Training on Molecular Markers of Lipogenesis and Lipid Partitioning in Fructose-Induced Liver Fat Accumulation

Table 3

Body weight, energy intake, sum of intra-abdominal fat pad weights (mesenteric, urogenital, and retroperitoneal), sum of 4 muscle weights (soleus, plantaris, medial, and lateral gastrocnemius), plasma glucose, insulin, and leptin in sedentary (Sed) and trained (TR) rats submitted to a fasting/refeeding protocol. Animals were fed a standard (SD) diet during 7 wks and thereafter were starved for 24 h and fed a SD diet for 24 h and starved for another 24 h and then fed the SD or the high-fructose (HFr) diet 24 h prior to sacrifice at the end of the 8th week.

DietsSD dietHFr diet
SedTRSedTR

Body weight (g)281 ± 8292 ± 8287 ± 9291 ± 7
Energy intake (kcal/last 24 h)84.7 ± 2.988.2 ± 4.2+57.9 ± 4.5&&74.9 ± 4.9&&,+
Sum of intra-abdominal fat pad weights (g)16.12 ± 1.915.2 ± 1.6+ ( 𝑃 = 0 . 0 5 8 )21.3 ± 2.3714.8 ± 1.58+ ( 𝑃 = 0 . 0 5 8 )
Sum of 4 muscle weights (g)1.96 ± 0.052.08 ± 0.05+1.97 ± 0.042.07 ± 0.05+
Plasma glucose (mmol/L)7.7 ± 0.38.1 ± 0.38.1 ± 0.47.3 ± 0.2
Plasma insulin (pM)456 ± 67573 ± 66437 ± 65447 ± 59
Plasma leptin (ng/mL)2.62 ± 0.42.26 ± 0.2+3 ± 0.42.02 ± 0.2+

Values are means ± SE, 𝑛 = 1 0 rats/group.
&&Significantly different from corresponding values under the SD diet, 𝑃 < 0 . 0 1 . +Significantly different from Sed rats under the same diet condition, 𝑃 < 0 . 0 5 .