The Effect of Neonatal Leptin Antagonism in Male Rat Offspring Is Dependent upon the Interaction between Prior Maternal Nutritional Status and Post-Weaning Diet

Figure 3

(a) Absolute body weights in male offspring from birth until weaning and (b) changes in neonatal body weights (grams, shown as delta difference in body weight between LA and Sal treated offspring, ΔLA-Sal) in CON and MHF neonates from birth until the time of weaning (day 22). Arrows indicate time of injection with LA at neonatal days 3, 5, and 7. 𝑃<0.005 for effect of LA treatment; maternal diet × LA treatment interaction 𝑃<0.05. 𝑁 = minimum 16 per group.

(a)

(b)