Table 2: Summary of key evidence.

Risk factorNumber of studiesNumber of participants (M/F)Size of effectQuality of evidence

Insulin sensitivity11161 (118/43)Moderate-to-LargeModerate quality
Triglycerides481 (65/16)Moderate-to-LargeModerate quality
Glucose tolerance6119 (83/36)Moderate-to-LargeModerate quality
HDL-cholesterol351 (35/16)ModerateVery low quality
Fasting insulin14207 (187/20)Small-to-ModerateVery low quality
Fasting glucose17191 (163/28)Small-to-ModerateVery low quality
LDL-cholesterol228 (22/6)ModerateVery low quality