Maternal Hyperglycemia Disrupts Histone 3 Lysine 36 Trimethylation of the IGF-1 Gene

Figure 3

Maternal hyperglycemia decreased hepatic IGF-1 mRNA variants in males. DOL 21 OHM hepatic mRNA variants were expressed as mean ± standard error of the mean relative to GAPDH, for female (F) and male (M) offspring, CON in white bars and OHM in grey bars, 𝑛=4 CON female, 𝑛=3 OHM female, 𝑛=5 CON male, and𝑛=3 OHM male. *𝑃<0.05.