Figure 4: Maternal hyperglycemia decreased H3Me3K36 along the length of the IGF-1 gene in males. (a) Female IGF-1 histone modifications in control animals expressed as a mean percent of P1 ± standard error of the mean. (b) Female IGF-1 histone modifications in OHM animals expressed as a mean percent of gender matched control values ± standard error of the mean. (c) Male IGF-1 histone modifications in control animals expressed as a mean percent of P1 ± standard error of the mean. (d) Male IGF-1 histone modifications in OHM animals expressed as a mean percent of gender matched control values ± standard error of the mean, CON female, OHM female, CON male, and OHM male. ; **; ***; ****.