Research Article

Partial Replacement with Menhaden Oil Improves Peripheral Neuropathy in High-Fat-Fed Low-Dose Streptozotocin Type 2 Diabetic Rat

Table 3

Effect of partial menhaden oil substitution in the diet of high-fat/streptozotocin diabetic rats on change in body weight, blood glucose, hemoglobin A1C, and epididymal fat pad.

DeterminationControl (10)Diabetic (10)Diabetic + menhaden oil (10)

Start weight (g) 3 1 6 ± 2 3 0 6 ± 2 3 0 9 ± 2
End weight (g) 5 0 5 ± 9 5 0 3 ± 1 6 4 6 1 ± 2 7
Blood glucose (mg/dL) 1 5 8 ± 6 3 5 1 ± 3 9 a 4 0 0 ± 3 7 a
Hb A1C (%) 8 . 9 ± 0 . 3 1 6 . 6 ± 0 . 9 a 1 4 . 0 ± 1 . 0 a
Epididymal fat pad (g) 6 . 6 ± 0 . 4 9 . 2 ± 0 . 8 a 6 . 6 ± 0 . 8

Data are presented as the mean ± S.E.M. a 𝑃 < 0 . 0 5 compared to control. Parentheses indicate the number of experimental animals.