Hyperleptinemia, Adiposity, and Risk of Metabolic Syndrome in Older Adults

Table 5

Adjusted odd ratios (OR) of metabolic syndrome by BMI category.

	BMI ≤ 25 (normal)	BMI > 25 (high)
Men (n)	210	372
Mean serum leptin (ng/mL) (mean ± SD)	4.61 (±3.5)	8.44 (±6.3)
Metabolic syndrome cases (n)	18	91
OR (95% CI)	1.08 (0.49−2.40)	1.32 (0.90−1.94)
Women (n)	267	329
Mean serum leptin (ng/mL) (mean ± SD)	11.44 (±8.8)	24.50 (±13.6)
Metabolic syndrome cases (n)	37	91
OR (95% CI)^1,2	2.10 (1.20−3.67)	2.00 (1.22−3.26)

1Adjusted for age, race, site, years of education, alcohol use, smoking, and physical activity.
2Odd ratios refer to the association of leptin with increased risk of metabolic syndrome among women with BMI ≤ 25 and those with BMI above 25.