Saturated Fatty Acid-Induced Cytotoxicity in Liver Cells Does Not Involve Phosphatase and Tensin Homologue Deleted on Chromosome 10
Figure 2
ER stress markers in H4IIE and HepG2 liver cells. XBP1 mRNA splicing (a), phosphorylation of eIF2α (b), and GRP78 protein expression (c) in H4IIE (left column) and HepG2 (right column) liver cells following 16 h of incubations with control media (LG) or fatty acids (oleate (O), linoleate (L), palmitate (P), or stearate (S)) at 250 μM in the absence (Control) or presence of PTEN knockdown (SiRNA) (). *: significantly () different from LG and O250.
