Saturated Fatty Acid-Induced Cytotoxicity in Liver Cells Does Not Involve Phosphatase and Tensin Homologue Deleted on Chromosome 10

<table>Effects of PTEN knockdown on phosphorylation of Akt in liver cells. Total Akt (a) and phosphorylated Akt (b)) in H4IIE (left column) and HepG2 (right column) liver cells following 16 h of incubations with control media (LG) or fatty acids (oleate (O) or palmitate (P)) at 250 <i>μ</i>M. Following incubations, cells were either treated (+ insulin) or not treated (− insulin) with 1 nM insulin for 30 minutes (<svg height="11.225" id="M9" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.225" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) different from corresponding scrambled SiRNA group. </table>

Journal of Nutrition and Metabolism

fig4

Figure 4

Figure 4: Saturated Fatty Acid-Induced Cytotoxicity in Liver Cells Does Not Involve Phosphatase and Tensin Homologue Deleted on Chromosome 10 