Timing of Maternal Exposure to a High Fat Diet and Development of Obesity and Hyperinsulinemia in Male Rat Offspring: Same Metabolic Phenotype, Different Developmental Pathways?

Table 2

Correlations between SOCS3 and other key genes. N = 8–13 per group.

	CONT	MHF	PLHF
SOCS3 versus ObRb	𝑅^2 = 0.69, P = 0.08	𝐑^𝟐 = 0.87, P = 0.0008	𝑅^2 = 0.03, P = 0.64
SOCS3 versus IR	𝐑^𝟐 = 0.67, P = 0.02	𝑅^2 = 0.02, P = 0.71	𝑅^2 = 0.002, P = 0.90
SOCS3 versus IRS1	𝐑^𝟐 = 0.84, P = 0.01	𝐑^𝟐 = 0.58, P = 0.02	𝑅^2 = 0.04, P = 0.51
SOCS3 versus IRS2	𝐑^𝟐 = 0.98, P = 0.002	𝐑^𝟐 = 0.58, P = 0.02	𝑅^2 = 0.15, P = 0.21
SOCS3 versus Kir6.2 channel	𝐑^𝟐 = 0.82, P = 0.03	𝐑^𝟐 = 0.93, P  < 0.0001	𝑅^2 = 0.002, P = 0.90
SOCS3 versus Pdx1	𝐑^𝟐 = 0.78, P = 0.009	𝐑^𝟐 = 0.91, P = 0.0003	𝑅^2 = 0.07, P = 0.40