Effects of High Phosphorus Diet on Bone Metabolism-Related Gene Expression in Young and Aged Mice

Table 2

Body weight, serum Ca and P, serum PTH, and markers of bone turnover.

	Young		Aged		Two-way ANOVA^1
	Control	High P	Control	High P
Initial body weight (g)	44.10 ± 0.79^A	44.20 ± 0.65^A	52.71 ± 2.17^B	53.84 ± 2.56^B	A
Final body weight (g)	48.66 ± 1.43	46.18 ± 0.67	51.47 ± 2.28	50.69 ± 2.19
Serum Ca (mg/dL)	9.15 ± 0.17	8.67 ± 0.20	8.81 ± 0.27	8.60 ± 0.12
Serum P (mg/dL)	9.23 ± 0.41	9.49 ± 0.47	9.07 ± 0.68	9.08 ± 0.60
Serum PTH (pg/mL)	52.8 ± 12.5^A	181.4 ± 33.0^B	76.7 ± 13.8^A	306.1 ± 51.1^C	P, A
Serum OC (ng/mL)	26.58 ± 0.83^A	37.53 ± 2.94^B	7.31 ± 0.48^C	13.44 ± 0.78^D	P, A
Urine CTx (g/mmol creatinine)	5.98 ± 0.91^A	16.73 ± 1.22^B	5.62 ± 1.02^A	9.61 ± 1.13^C	P, A, P × A

The data indicate the mean ± SEM of 6 mice.
The different superscript letters denote significant differences ().
¹Significant effect (): P = effect of high P diet; A = effect of age; P × A = effect of interaction.