A Comparative Study of the Metabolic and Skeletal Response of C57BL/6J and C57BL/6N Mice in a Diet-Induced Model of Type 2 Diabetes

Figure 3

Glucose tolerance test results following 24 wk on control or high fat diet. One week prior to the end of the study, an intraperitoneal glucose tolerance test was administered (2 g glucose/kg body weight) in the C57BL/6J, C57BL/6N, and C3H/HeJ mice fed a control (Con; AIN-93M) or a high fat diet (HF; 45% kcal from fat). (a) Tail blood was collected following 15, 30, 60, 90, and 120 min following glucose injection and symbols, for C57BL/6J, † for C57BL/6N, or § C3H/HeJ, indicate significant differences () of dietary treatment for a given mouse strain. (b) Area under the curve (AUC) was calculated for the IGTT and symbol, , represents a significant difference () between dietary treatments for a given strain.

(a)

(b)