Omega-3 Fatty Acids: Possible Neuroprotective Mechanisms in the Model of Global Ischemia in Rats

Figure 1

Evaluations of the number of crossing (a) and rearing (b) behaviors by the open field test. The columns represent means ± SEM (number of crossings/5 min) from SO and rats subjected to cerebral ischemia untreated or after oral treatments with 3, at the doses of 5 and 10 mg/kg (number of animals per group: SO = 27; ISC = 35; ISC + ω3 (5) = 14; ISC + ω3 (10) = 17). (a) (A) versus SO, q = ; (B) versus ISC + 3 (5), q = ; (C) versus ISC + 3 (10), q = ; (D) versus SO, q = . (b) (A) versus SO, q = ; (B) versus ISC + 3 (5), q = ; (C) versus ISC + 3 (10), q = (one-way ANOVA and Newman-Keuls test as the post hoc test).

(a)

(b)