Recent Advancement in Functional Core-Shell Nanoparticles of Polymers: Synthesis, Physical Properties, and Applications in Medical Biotechnology
Figure 31
Fluorescence imaging of HeLa cells after incubated with rabbit anti-CEA8 Ab-conjugated UCNPs (a), amino-modified NPs without linking any antibody (b), and rabbit anti-goat Ab-conjugated UCNPs (c) for 1 h. Left rows are images in bright field; the middle rows are fluorescent images in dark field; and right rows are overlays of the left and middle rows [88].