Magnetic Fluid Hyperthermia of Rodent Tumors Using Manganese Perovskite Nanoparticles

Table 1

Results of nanohyperthermia influence on rat’s solid tumors.

Tumor	Index of tumor growth inhibition (by -fold)	Tumor growth delay (day)	Number of rats with complete tumor regression (%)	Number of cured rats (%)*
Guerin carcinoma
Untreated control ()	0	0	0	0
Nanohyperhermia ()	3.7	10.3 ± 1.2	35**	25**
Walker-256 carcinosarcoma
Untreated control ()	0	0	0	0
Nanohyperthermia ()	3.2	6.0 ± 1.0	15	0

*Rats with complete tumor regression and without tumor recurrence within 120 days after complete regression of tumor.
**Thermoablation effect was observed that resulted in the complete regression of tumor and absence of tumor recurrence. It has to be noted that this effect (thermoablation) is not observed after application of microwave hyperthermia (43-44°C within 60 min; our data).
: number of rats.