Research Article

FOLDNA, a Web Server for Self-Assembled DNA Nanostructure Autoscaffolds and Autostaples

Figure 2

Examples for DNA nanostructure design. (a) left column: object picture; middle column: monochrome image, user uploaded; right column: digitized image, according to the user uploaded image. (b, c, d), wet-lab products observed by AFM. Uploaded image and digitized image are screenshots from our web server. In the digitized images, scaffold ssDNA forms seams on the border and along the red lines. The selected shapes for validation are a hexagon, a rabbit and a panda (a). The corresponding results are (b), (c) and (d). The pathways for the scaffold and staple DNA as well as the sequence lists for staple DNA we used for wet-lab experiments are shown in the Supplementary Materials (see Supplementary Materials available online at doi:10.1155/2012/453953).
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