Table 4: Pharmacokinetic parameters for praziquantel in rats after oral administration of PZQ-SLNs and PZQ suspension at an equivalent praziquantel dose of 50 mg/kg (values are means SD, ).

Formulation (h) (µg/mL) (μg h/mL)MRT (h) (h)

PZQ suspension0.17 2.67
PZQ-SLN (F25)0.33 14.18