Research Article
Cyclosporine A Loaded PLGA Nanoparticles for Dry Eye Disease: In Vitro Characterization Studies
Table 5
Zeta potential and percent entrapment efficiency of different PLGA loaded NPs.
| | NPs Code | Factor
A | Factor
B | Zeta potential (mV) in UPW | Zeta potential
(mV) in SLF | Entrapment efficiency
(% E.E) |
| | F1 | 25 | 25 | +20.3 ± 6.4 | +16.4 ± 5.2 | 58.35 ± 2.4 | | F2 | 50 | 25 | +21.0 ± 2.3 | +18.6 ± 2.1 | 63.41 ± 3.2 | | F3 | 75 | 25 | +24.7 ± 1.5 | +22.3 ± 1.4 | 91.69 ± 1.4 | | F4 | 25 | 50 | +25.6 ± 3.2 | +15.9 ± 3.7 | 59.65 ± 2.3 | | F5 | 50 | 50 | +25.2 ± 4.7 | +19.8 ± 4.3 | 86.37 ± 1.7 | | F6 | 75 | 50 | +24.0 ± 5.0 | +21.0 ± 4.8 | 88.96 ± 1.73 | | F7 | 25 | 75 | +32.5 ± 5.4 | +26.2 ± 5.3 | 60.21 ± 3.4 | | F8 | 50 | 75 | +31.8 ± 5.9 | +24.2 ± 6.0 | 85.66 ± 2.72 | | F9 | 75 | 75 | +34.5 ± 4.8 | +30.4 ± 5.9 | 89.65 ± 2.6 |
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Data as mean ± SD, .
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