Plant-Mediated Green Synthesis of Ag NPs and Their Possible Applications: A Critical Review

Table 2

Morphology of green synthesized Ag NPs and their antiviral activity on different viral strains.

Phytoconstituents	Size by TEM/SEM with morphology	Viral strain	Antiviral activity (IC50/MNTD/TCID50/ml)	Reference
Alkaloids, terpenoids, flavonoids, glycosides, phenols, and tannins	TEM 27.89 nm; Spherical in shape		IC50	[127]
		HSV-1	36.36 μg/ml
		HAV-10	11.71 μg/ml
		CoxB4	12.24 μg/ml
Polyols, flavonoids, polyphenols, and terpenoids	SEM average size 70–95 nm	Chikungunya	MNTD: 31.25 μg/mL	[4]
Polyphenols	SEM average size 100 nm; Spherical in shape	Dengue (DEN-2)	TCID50/ml	[128]
			Viral titer; 3.2 log10 at 20 μl/ml Ag NPs
Lignocellulose	TEM 3–10 nm; Narrow in shape	Chikungunya	IC50: 11.73 μg/ml	[129]
—	SEM average size 42 nm; Spherical in shape	H7N3 influenza virus	IC50: 101 μg/ml (during viral infection) and 125 μg/ml (after viral infection)	[130]