Interaction among Skeletal Muscle Metabolic Energy Systems during Intense Exercise
Figure 3
The urea cycle of the liver, showing the connections between the TCA cycle in the mitochondria, ammonia, and the production of urea. Note that the conversion of glutamate to α-ketoglutarate (top central region of figure) is condensed for clarity [aspartate aminotransferase]) and is therefore also a source of aspartate. The direct conversion of glutamate to α-ketoglutarate is catalyzed by glutamate dehydrogenase.