Strong Expression of Chemokine Receptor CXCR4 by Renal Cell Carcinoma Correlates with Advanced Disease

Table 1

Patient and tumor characteristics dependent on intensity of CXCR4 expression.

	CXCR4 expression			Statistics
	Weak	Medium	Strong
Total number	39 (34%)	47 (42%)	27 (24%)
Average age (years)	63.8		66.3	n.s.
Gender
Female	36 (42%)		8 (30%)	n.s.
Male	50 (58%)		19 (70%)
Grading
1/2	65 (78%)		11 (41%)	𝑃=.0005
3/4	18 (22%)		15 (59%)
T-status
1/2	64 (76%)		15 (56%)	𝑃=.039
3/4	20 (24%)		12 (44%)
Average size (cm)	5.7		6.0	n.s.
Survival (months)	29.7		36.8	n.s.
Average creatinin (mg/dl)	1.11		1.07	n.s.
Average hemoglobin (g/dl)	14.32		13.25	𝑃=.019(1-sided)
				𝑃=.039(2-sided)
Average thrombocytes (/nl)	271		313	𝑃=.089(1-sided)
				𝑃=.18(2-sided)